Residual dipolar coupling enhanced NMR spectroscopy and chiroptics: a powerful combination for the complete elucidation of symmetrical small molecules.
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چکیده
منابع مشابه
Investigation of molecular motion of Cl-adamantane in the nanoprous zeolite by 13C NMR dipolar dephasing and variable contact time measurements
Dipolar-dephasing method provides some information about the strength of dipolar coupling in solids. Dipolar dephasing technique measures the time for a polarized carbon nucleus to lose its magnetization once the proton locking field is terminated. The dynamics of guest molecules adsorbed within the cavities and channels of nonporouszeolite strongly depend on the structure and chemical composit...
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Together with NOE and J coupling, one-bond residual dipolar coupling (RDC), which reports on the three-dimensional orientation of an internuclear vector in the molecular frame, plays an important role in the conformation and configuration analysis of small molecules in solution by NMR spectroscopy. When the molecule has few C-H bonds, or too many bonds are in parallel, the available RDCs may no...
متن کاملInvestigation of molecular motion of Cl-adamantane in the nanoprous zeolite by 13C NMR dipolar dephasing and variable contact time measurements
Dipolar-dephasing method provides some information about the strength of dipolar coupling in solids. Dipolar dephasing technique measures the time for a polarized carbon nucleus to lose its magnetization once the proton locking field is terminated. The dynamics of guest molecules adsorbed within the cavities and channels of nonporouszeolite strongly depend on the structure and chemical composit...
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We illustrate how moderate resolution protein structures can be rapidly obtained by interlinking computational prediction methodologies with un- or partially assigned NMR data. To facilitate the application of our recently described method of ranking and subsequent refining alternative structural models using unassigned NMR data [Proc. Natl. Acad. Sci. USA 100 (2003) 15404] for such "structural...
متن کاملStereochemistry determination by powder X-ray diffraction analysis and NMR spectroscopy residual dipolar couplings.
Traditional techniques for stereochemistry analysis have limitations; for example solution NMR spectroscopy has spatial limitation for the transference of stereochemical information, and suitable single crystals for X-ray analysis may not be available. Residual dipolar coupling (RDC) and powder X-ray diffraction (PXRD) are both techniques whose use is not yet widespread. We report a double-blin...
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ورودعنوان ژورنال:
- Chemistry
دوره 17 43 شماره
صفحات -
تاریخ انتشار 2011